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ZepHr® Impedance/pH Reflux Monitoring System

Selecting the appropriate Reflux Monitoring Test for your patients is more important than ever.

Reflux monitoring, whether pH or impedance/pH, has advantages and drawbacks. The recently updated ACG Practice Guidelines for Diagnosis and Management of GERD provide a simple, yet comprehensive reflux monitoring test selection algorithm1.

What to know about reflux monitoring.

While an empiric PPI trial remains the first-line diagnostic test in suspected GERD patients, nearly 40% of these patients on PPI treatment continue to experience symptoms2.

  • A second-line diagnostic test, upper endoscopies are appropriate to determine the extent of esophageal damage. However, over 70% of these are negative3.
  • Today’s clinicians have additional diagnostic tools available to help them understand these endoscopy-negative patients with persistent symptoms.

When to choose impedance/pH monitoring?

Patients on PPIs who continue to experience symptoms such as cough, heartburn, regurgitation and chest pain are often difficult to diagnose using traditional pH monitoring. These PPI-refractory, endoscopy-negative patients are optimal candidates for impedance/pH reflux monitoring. In fact, physicians using only acid pH monitoring may miss up to 35% of patients with non-acid reflux.

  • The sensitivity of pH-only monitoring in patients with endoscopy-negative reflux symptoms is <71%.
  • According to a consensus study by Sifrim et al, when impedance testing is added to pH monitoring, the sensitivity of reflux monitoring approaches 90%4.

 

Selecting the appropriate Reflux Monitoring Test for your patients is more important than ever.

Reflux monitoring, whether pH or impedance/pH, has advantages and drawbacks. The recently updated ACG Practice Guidelines for Diagnosis and Management of GERD provide a simple, yet comprehensive reflux monitoring test selection algorithm1.

What to know about reflux monitoring.

While an empiric PPI trial remains the first-line diagnostic test in suspected GERD patients, nearly 40% of these patients on PPI treatment continue to experience symptoms2.

  • A second-line diagnostic test, upper endoscopies are appropriate to determine the extent of esophageal damage. However, over 70% of these are negative3.
  • Today’s clinicians have additional diagnostic tools available to help them understand these endoscopy-negative patients with persistent symptoms.

When to choose impedance/pH monitoring?

Patients on PPIs who continue to experience symptoms such as cough, heartburn, regurgitation and chest pain are often difficult to diagnose using traditional pH monitoring. These PPI-refractory, endoscopy-negative patients are optimal candidates for impedance/pH reflux monitoring. In fact, physicians using only acid pH monitoring may miss up to 35% of patients with non-acid reflux.

  • The sensitivity of pH-only monitoring in patients with endoscopy-negative reflux symptoms is <71%.
  • According to a consensus study by Sifrim et al, when impedance testing is added to pH monitoring, the sensitivity of reflux monitoring approaches 90%4.

ZepHr Impedance/pH Recorder

  • Small size and weight
  • Upright and recumbent indicators for easy viewing, easy interface
  • SD Card for quick, effortless data download
  • Only needs 2 AA batteries and includes a cleanable carrying case

ComforTEC® Z/pH Probes

  • Enhanced patient comfort
  • Optimal ease-of-use
  • The widest range of standard configurations to meet your clinical need
  • Small diameter for easy insertion
  • Made from specially-formulated materials that soften in response to body temperature
  • High-quality, single-use
  • 100% guaranteed performance
  • A variety of esophageal lengths to accommodate any size patient
  • Single branch LPR probes with both distal and proximal pH and impedance sensors to identify and characterize acid and nonacid LPR